MovDisordV3, Main, Exploration, bibRecord, 000795

Response Inhibition in Motor Conversion Disorder

Identifieur interne : 000795 ( Main/Exploration ); précédent : 000794; suivant : 000796

Response Inhibition in Motor Conversion Disorder

Auteurs : Valerie Voon [Royaume-Uni, États-Unis] ; Vindhya Ekanayake [États-Unis] ; Edythe Wiggs [États-Unis] ; Sarah Kranick [États-Unis] ; Rezvan Ameli [États-Unis] ; Neil A. Harrison [Royaume-Uni] ; Mark Hallett [États-Unis]

Source :

Movement disorders : official journal of the Movement Disorder Society [ 0885-3185 ] ; 2013.

RBID : PMC:4096145

English descriptors

KwdEn :
- Adult, Case-Control Studies, Cognition Disorders (etiology), Conversion Disorder (complications), Conversion Disorder (psychology), Female, Humans, Inhibition (Psychology), Male, Memory Disorders (etiology), Middle Aged, Movement Disorders (complications), Movement Disorders (psychology), Neuropsychological Tests, Reaction Time, Verbal Learning (physiology).
MESH :
- complications : Conversion Disorder, Movement Disorders.
- etiology : Cognition Disorders, Memory Disorders.
- physiology : Verbal Learning.
- psychology : Conversion Disorder, Movement Disorders.
- Adult, Case-Control Studies, Female, Humans, Inhibition (Psychology), Male, Middle Aged, Neuropsychological Tests, Reaction Time.

Abstract

Conversion disorders (CDs) are unexplained neurological symptoms presumed to be related to a psychological issue. Studies focusing on conversion paralysis have suggested potential impairments in motor initiation or execution. Here we studied CD patients with aberrant or excessive motor movements and focused on motor response inhibition. We also assessed cognitive measures in multiple domains. We compared 30 CD patients and 30 age-, sex-, and education-matched healthy volunteers on a motor response inhibition task (go/no go), along with verbal motor response inhibition (color-word interference) and measures of attention, sustained attention, processing speed, language, memory, visuospatial processing, and executive function including planning and verbal fluency. CD patients had greater impairments in commission errors on the go/no go task (P <.001) compared with healthy volunteers, which remained significant after Bonferroni correction for multiple comparisons and after controlling for attention, sustained attention, depression, and anxiety. There were no significant differences in other cognitive measures. We highlight a specific deficit in motor response inhibition that may play a role in impaired inhibition of unwanted movement such as the excessive and aberrant movements seen in motor conversion. Patients with nonepileptic seizures, a different form of conversion disorder, are commonly reported to have lower IQ and multiple cognitive deficits. Our results point toward potential differences between conversion disorder subgroups.

Url:

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4096145

DOI: 10.1002/mds.25435
PubMed: 23554084
PubMed Central: 4096145

Affiliations:

Le document en format XML

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<term>Conversion Disorder (psychology)</term>
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<term>Inhibition (Psychology)</term>
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<keywords scheme="MESH" qualifier="psychology" xml:lang="en"><term>Conversion Disorder</term>
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<front><div type="abstract" xml:lang="en"><p id="P1">Conversion disorders (CDs) are unexplained neurological symptoms presumed to be related to a psychological issue. Studies focusing on conversion paralysis have suggested potential impairments in motor initiation or execution. Here we studied CD patients with aberrant or excessive motor movements and focused on motor response inhibition. We also assessed cognitive measures in multiple domains. We compared 30 CD patients and 30 age-, sex-, and education-matched healthy volunteers on a motor response inhibition task (go/no go), along with verbal motor response inhibition (color-word interference) and measures of attention, sustained attention, processing speed, language, memory, visuospatial processing, and executive function including planning and verbal fluency. CD patients had greater impairments in commission errors on the go/no go task (<italic>P</italic>
 <.001) compared with healthy volunteers, which remained significant after Bonferroni correction for multiple comparisons and after controlling for attention, sustained attention, depression, and anxiety. There were no significant differences in other cognitive measures. We highlight a specific deficit in motor response inhibition that may play a role in impaired inhibition of unwanted movement such as the excessive and aberrant movements seen in motor conversion. Patients with nonepileptic seizures, a different form of conversion disorder, are commonly reported to have lower IQ and multiple cognitive deficits. Our results point toward potential differences between conversion disorder subgroups.</p>
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Movement Disorders (revue)

Response Inhibition in Motor Conversion Disorder

Response Inhibition in Motor Conversion Disorder

Source :

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki

	Movement Disorders (revue)
	Attention, ce site est en cours de développement ! Attention, site généré par des moyens informatiques à partir de corpus bruts. Les informations ne sont donc pas validées.